Intraocular Lens (IOL): Market Shares, Strategies, and Forecasts, Worldwide, Nanotechnology, 2013 to 2018

Intraocular Lens (IOL) Executive Summary

Intraocular Lens Market Driving Forces

Cataract Surgical Technology Is Evolving Rapidly

Patient Populations Have Significant Demand for Cataract Surgery

Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved

Cataract Surgery Business

Intraocular Lens Market Challenges

World Population Growth

Intraocular Lens Market Shares

Intraocular Lens Market Forecasts

1.Intraocular Lens Market Description and Market Dynamics

1.1 Cataract Surgical Technology Is Evolving Rapidly

1.1.1 Patient Populations Have Significant Demand for Cataract Surgery

1.1.2 Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved

1.1.3 Cataract Surgery Business

1.1.4 Intraocular Lens Market Challenges

1.2 World Economy Undergoing A Transformation

1.2.1 Global Economic Conditions:

1.2.2 Global Economy Becomes Steadily More Sluggish

1.2.3 Global Economic Conditions Impact Markets

2. Intraocular Lens Market Shares and Forecasts

2.1 Intraocular Lens Market Driving Forces

2.1.1 Cataract Surgical Technology Is Evolving Rapidly

2.1.2 Patient Populations Have Significant Demand for Cataract Surgery

2.1.3 Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved

2.1.4 Cataract Surgery Business

2.1.5 Intraocular Lens Market Challenges

2.1.6 World Population Growth

2.2 Intraocular Lens Market Shares

2.2.1 Novartis / Alcon

2.2.2 Novartis / Alcon Competitive Situation

2.2.3 Novartis / Alcon Competition

2.2.4 Novartis Alcon Multifocal Lenses

2.2.5 Novartis / Alcon

2.2.6 Novartis / Alcon

2.2.7 Novartis / Alcon AcrySof® Toric Intraocular Lens - (IOL) – FDA Approval P930014/S045

2.2.8 LenSx Acquired by Alcon

2.2.9 Abbott Medical Optics

2.2.10 Abbott Medical Optics / Visiogen’s Synchrony

2.2.11 Abbott Tecnis

2.2.12 Abbott TECNIS® IOLs

2.2.13 Bausch & Lomb Presbyopic IOLs

2.2.14 Bausch + Lomb

2.2.15 Bausch + Lomb Eye Surgical Technologies In The Pipeline

2.2.16 Bausch + Lomb: Accommodating IOLs

2.2.17 Bausch + Lomb:  Crystalens IOL

2.2.18 OptiMedica

2.2.19 Staar Acrylic IOL

2.2.20 Staar

2.2.21 Staar Silicone IOLs

2.2.22 Staar® Surgical Company nanoFLEX IOL

2.2.23 Staar Visian

2.2.24 LensAR

2.2.25 PhysIOL's FineVision

2.2.26 IOL Research and New Lenses

2.2.27 ReSTOR Multifocal Toric AcrySof IQ

2.2.28 Abbott Tecnis One-Piece Toric

2.2.29 Lenstec Tetraflex

2.2.30 Calhoun Vision Light-Adjustable Lens

2.2.31 Abbott Visiogen Synchrony

2.2.32 Rayner M-flex T

2.2.33 NuLens DynaCurv

2.2.34 Carl Zeiss AcriLisa Diffractive Multifocal Toric

2.2.35 Bausch + Lomb’s Crystalens Toric

2.2.36 Hoya’s Adoptics

2.3 Intraocular Lens Market Forecasts

2.3.1 Intraocular Lens Market Segment Forecasts

2.3.2 Number of Cataract Surgeries Per Year

2.3.3 Novartis Positioning with Sales and Marketing Resource

2.3.4 Bausch + Lomb Small Incisions

2.3.5 Femtosecond Technology Is Game Changer

2.3.6 Intraocular Lens Unit Analysis

2.3.7 Aspheric Foldable IOL Lens

2.3.8 Intraocular Lens Presbyopia Market Forecasts

2.3.9 Market Trend:  Monofocal IOL Channel Will Be Slowly But Continuously Eroded By The Multifocal IOL

2.3.10 Presbyopia-Correcting Intraocular Lens (IOL)

2.3.11 Premium Channel Surgeons

2.3.12 Market Trend:  Accommodating IOL Channel to Grow

2.3.13 Market Trends:  Diffractive Lenses

2.3.14 Market Trend:  Multifocal IOLs

2.3.15 Market Trend:  Surgical Workstation

2.3.16 Premium IOL Forecasts

2.3.17 Technologies Driving Intraocular Lens IOL Market Growth

2.3.18 Diffractive IOLs

2.3.19 Large Middleclass Population Base Driving Intraocular Lens IOL Market Growth

2.3.20 Nonfoldable Polymethylmethacrylate/Plexiglas Based Lenses To Silicone And Acrylic Based Foldable Lenses

2.3.21 Global Vision Care and Ocular Market

2.4 Intraocular Lens Prices

2.4.1 Premium Lens Technology Reimbursement Trends

2.4.2 CMS Medicare Intorocular Reimbursement Guidelines

2.5 Intraocular Lens Regional Market

2.5.1 Eye Surgical Techniques by Country

2.5.2 United States

2.5.3 Canada

2.5.4 Brazil Cataract Surgical Procedure

2.5.5 Brazilian  Cataract surgeries

2.5.6 China

2.5.7 Toric Lens Implantations On The Rise In Europe

2.5.8 Advanced Technology Intraocular Lens Growth Markets

2.5.9 Cataract Surgery in the UK

2.5.10 Asia-Pacific Cataract Surgery

2.5.11 Cataract Surgery in India

2.5.12 Cataract Surgery Assembly Line System Followed At Aravind Eye Hospitals

2.5.13 Aurolab’s Low-Cost, High-Volume Business Model

2.5.14 Highly Efficient Operations Coupled With Pricing Structure Allow 50% Profit Margin

2.5.15 World Health Organization (WHO),

3. Intraocular Lens (IOL) Product Description

3.1 IOL lenses

3.2 Novartis / Alcon

3.1.1 Novartis / Alcon

3.1.2 Novartis / Alcon Competitive Situation

3.1.3 Novartis / Alcon Competition

3.1.4 Novartis Alcon Multifocal Lenses

3.1.5 Novartis / Alcon

3.1.6 Novartis / Alcon

3.1.7 Novartis / Alcon AcrySof® Toric Intraocular Lens - (IOL) – FDA Approval P930014/S045

3.1.8 LenSx Acquired by Alcon

3.3 Abbott Medical Optics / Visiogen’s Synchrony

3.3.1 Abbott Medical Optics Synchrony

3.3.2 Abbott Medical Optics’

3.3.3 Abbott Medical Optics / Visiogen’s Synchrony Lens

3.4 Bausch & Lomb / Crystalens

3.4.1 Bausch & Lomb Crystalens AO Lens

3.4.2 Bausch + Lomb: Accommodating IOLs

3.4.3 Bausch + Lomb:  Crystalens IOL

3.4.4 Bausch & Lomb Crystalens HD

3.5 Calhoun Vision’s Light Adjustable Lens

3.6 NuLens

3.7 PixelOptics

3.8 Imperial Medical Technologies’

3.9 Presbia’s Flexivue

3.10 Lenstec’s Tetraflex Lens

3.11 Staar

3.11.1 STAAR® Surgical Company nanoFLEX IOL

3.11.2 Staar Elastimide® Silicone Aspheric IOL

3.11.3 Staar nanoFLEX™ Collamer Aspheric Single-Piece IOL

3.11.4 Staar Afinity™ Collamer® Aspheric IOL

3.11.5 STAAR Toric™ IOL

3.11.6 Staar Afinity™ and nanoFLEX™ Collamer Aspheric IOLs

3.11.7 Staar Collamer Advantage

3.11.8 Staar nanoFLEX™ Collamer Aspheric Single-Piece IOL

3.11.9 STAAR Surgical Elastimide Silicone Aspheric IOL Model AQ2015A

3.11.10 STAAR Elastimide Lens Model AQ2003V

3.11.11 STAAR Elastimide Lens Model AQ2010V

3.11.12 STAAR Elastimide Lens Model AQ5010V - Low Diopter

3.11.13 STAAR Elastimide Lens Model AQ2017V (Discontinued)

3.11.14 STAAR Elastimide Lens Model AQ1016V (Discontinued)

3.11.15 STAAR Elastic Lens Model AA4204VF

3.11.16 STAAR Elastic Lens Model AA4204VL

3.11.17 STAAR Elastic Lens Model AA4207VF (Discontinued)

3.11.18 STAAR Toric Silicone Single Piece IOL

3.11.19 STAAR Elastic Toric Lens Model AA4203TL

3.11.20 Canon-STAAR Preloaded IOL Model KS-3Ai

3.12 Lxenstec’s Tetraflex

3.12.1 Lxenstec’s Tetraflex Manufactured To A Tenth Of A Diopter Toleranc3-e

3.12.2 Lxenstec Elenza Lens

3.13 Hoya

3.14 Tecnis MF

3.14.1 PowerVision (Belmont, Calif.), Oculentis (Berlin), and PhysIOL (Liège, Belgium

3.14.2 PowerVision's FluidVision

3.14.3 FluidVision

3.15 MPlus by Oculentis

3.16 PhysIOL's FineVision

3.17 WaveTec Vision

3.18 Pediatric Cataract / Intraocular Lenses (IOL)

3.18.1 4 D change in power is needed between ages 10 and 20

3.18.2 Correcting Astigmatism in Pediatric Patients

4. Intraocular Lens (IOL) Technology

4.1 The Human Eye

4.2 Cataracts

4.2.1 Staar Collamer

4.2.2 Cataract Symptoms

4.2.3 Benefits Of Cataract Eye Surgery

4.2.4 How Cataract Eye Surgery Is Performed

4.3 Intraocular Tens Technology

4.3.1 Technologies Driving Intraocular Lens IOL Market Growth

4.4 Aspheric Contact Lenses

4.5 Refractive Disorders

4.6 Studies On The Restor Toric Lens

4.6.1 MNRead Functional Reading Test

4.7 Surgeons Need To Concentrate On Proper Patient Selection

4.8 Mayo Clinic Study of Long-Term Dislocation Of Intraocular Lenses

4.8.1 Obesity Cause of Diabetes and Neuropathy of the Eye

5. Intraocular Lens (IOL) Company Description

5.1 Abbott Laboratories

5.1.1 Abbott Acquired Visiogen with Synchrony Product

5.1.2 Abbott Labs Cataract Company Acquisitions

5.1.3 Abbott Completes Separation of Research-Based Pharmaceuticals Business

5.1.4 Abbott (NYSE: ABT) Separation Of Its Research-Based Pharmaceuticals Business

5.1.5 Abbott Separating Into Two Independent Companies

5.1.6 Abbott Laboratories and Subsidiaries Revenue

5.1.7 Abbott Sales Mix

5.1.8 Abbott Nutritional Market Presence

5.1.9 Abbott Diagnostics Market Presence

5.1.10 Abbott Medical Devices Market Presence

5.1.11 Abbott Strength Through Ability to Innovate

5.1.12 Abbott Revenue

5.1.13 Abbott Medical Optics

5.1.14 Abbott Medical Optics Corneal Products

5.1.15 Abbott Medical Optics Refractive Product Line

5.1.16 Abbott Medical Optics Cataract Products

5.1.17 Abbott Medical Optics Technological Innovation

5.2 Akkolens

5.2.1 AkkoLens Features

5.2.2 AkkoLens Clinical Partners

5.3 Allergan

5.3.1 Allergan Flagship Franchises In Eye Care, Neurosciences, Medical Dermatology And Urologics

5.3.2 Allergan Acquisition of Inamed Corporation

5.3.3 Allergan Specialty Product Lines Focused On High-Growth Markets

5.3.4 Allergan Global in reach. Specialized in focus

5.3.5 Allergan Leading Products

5.3.6 Allergan/  SkinMedica, Inc. Acquisition

5.3.7 Allergan Obesity Intervention

5.4 Aravind

5.4.1 Future of Aravind

5.5 Bausch And Lomb

5.5.1 Bausch + Lomb Vision Care

5.5.2 Bausch + Lomb Pharmaceuticals

5.5.3 Bausch + Lomb Cataract and Vitreoretinal Surgery

5.5.4 Bausch + Lomb to Acquire Technolas Perfect Vision GmbH

5.5.5 Bausch + Lomb Technolas® Perfect Vision

5.5.6 Bausch + Lomb Technolas® Perfect Vision Transforming Refractive Surgery

5.5.7 Bausch + Lomb to Acquire Technolas Perfect Vision GmbH

5.5.8 Technolas Perfect Vision

5.6 Biovision

5.7 Elenza

5.8 Kowa Company, Ltd. Environmental & Energy Saving Products

5.9 Hoya

5.9.1 Hoya, Seiko And Epson; Agreements Executed In The Field Of Optical Products Business

5.9.2 Hoya Second Quarter Revenue

5.10 Lenstec

5.11 Novartis Group / Alcon

5.11.1 Novartis Alcon Division

5.11.2 Novartis Revenue

5.11.3 Alcon Cataract Surgery

5.11.4 Alcon Surgical Glaucoma

5.11.5 Alcon Vitreoretinal

5.11.6 Alcon Refractive Surgery

5.11.7 Alcon Acquires Leading Ocular Surgical Guidance Technology

5.11.8 Alcon

5.11.9 Alcon Acquired The Ophthalmic Division of SensoMotoric Instruments (SMI)

5.11.10 Alcon Division Surgical Products

5.11.11 Alcon Ophthalmic Pharmaceuticals

5.11.12 Alcon Products

5.11.13 Alcon Cataract Reimbursement

5.11.14 Alcon Regulation

5.11.15 LenSx Acquired by Alcon

5.12 OptiMedica

5.12.1 Catalys next generation laser cataract surgery platform

5.13 Physiol

5.13.1 Physiol Multifocal IOL FineVision (Micro F) 2

5.14 Rayner

5.14.1 Surgery on 109 Year old Woman Using Rayner IOL

5.15 Staar Surgical

5.15.1 STAAR Surgical Devices Used In Corrective Surgery

5.15.2 STAAR Surgical Minimally Invasive Intraocular Lenses (IOLs).

5.16 WaveTec Vision®

5.16.1 WaveTec Vision Secures $16.5m To Market Cataract Surgery System

5.17 Zeiss –

5.17.1 Zeiss Vision

5.17.2 Zeiss Revenue

5.18 Selected Companies in the Market

List of Tables and Figures

Table ES-1 Intraocular Lens Market Driving Forces

Figure ES-2 Advanced Technology Intraocular Lens Growth Drivers

Table ES-2 Cataract Surgery Diverse Market Growth Drivers Several generations of IOLs have create significant technical advances in the market. Intraocular Lens market challenges are evolving in the context of this dramatic market shift.

Table ES-3 Intraocular Lens Market Challenges

Table ES-4 Intraocular Lens (IOL) Market Shares, Dollars, Worldwide,  2012

Figure ES-5 Intraocular Lens (IOL) Market Forecasts, Dollars, Worldwide, 2013-2019

Table 1-1 Cataract Surgery Diverse Market Growth Drivers

Table 1-2 Intraocular Lens Market Challenges

Table 2-1 Intraocular Lens Market Driving Forces

Figure 2-2 Advanced Technology Intraocular Lens Growth Drivers

Table 2-2 Cataract Surgery Diverse Market Growth Drivers Several generations of IOLs have created significant technical advances in the market. Intraocular Lens market challenges are evolving in the context of this dramatic market shift

Table 2-3 Intraocular Lens Market Challenges

Table 2-4 Intraocular Lens (IOL) Market Shares, Dollars, Worldwide,  2012

Table 2-5 Intraocular Lens (IOL) Market Shares, Dollars, Worldwide, 2012

Table 2-6 Novartis Cataract Surgical Techniques

Figure 2-7 Novartis / Alcon Overview of Surgical Franchise

Figure 2-8 Alcon Key Intraocular Lenses (IOLs) Products

Table 2-9 Novartis / Alcon IOL Market Strategic Positioning

Figure 2-10 Bausch + Lomb Crystalens® is an FDA-approved intraocular lens

Table 2-11 ReSTOR’s Acrylic Material Helps Keep It From Rotating Postop

Figure 2-12 Abbott Tecnis Toric IOL

Figure 2-13 Lenstec Tetraflex

Figure 2-14 Abbott Visiogen Synchrony

Figure 2-15 NuLens DynaCurv

Figure 2-16 Intraocular Lens (IOL) Market Forecasts, Dollars, Worldwide, 2013-2019

Table 2-17 Intraocular Lens Market Forecasts Units and Dollars, Worldwide, 2013-2019

Figure 2-18 Low End Intraocular Lens (IOL) Market Shipments Forecasts  Dollars, Worldwide, 2013-2019

Figure 2-19 Premium Intraocular Lens (IOL) Market Shipments  Forecasts Dollars, Worldwide, 2013-2019

Table 2-20 Intraocular Lens (IOL) Market Forecasts Units and Dollars, Worldwide, 2013-2019

Figure 2-21 Intraocular Lens (IOL), Market Forecasts, Units, Worldwide, 2013-2019

Figure 2-22 Novartis Franchise Dedicated Resources

Figure 2-23 Cataract Surgery Pathophysiology, Prevalence, and Surgical Techniques

Table 2-24 Intraocular Lens Description

Table 2-25 Intraocular Lens Advanced Technology

Figure 2-26 Novartis Commentary on Cataracts as Leading Cause of Reversible Blindness

Figure 2-27 Intraocular Lens (IOL) Regional Market Segments, Dollars,  2012

Table 2-28 Intraocular Lens (IOL) Regional Market Revenue Segments, US and Worldwide, Dollars Worldwide, 2013-2019

Table 2-29 Intraocular Lens (IOL) Regional Market Revenue Segments, US and Worldwide Percent, Worldwide, 2013-2019

Figure 2-30 Eye Surgical Techniques by Country

Figure 3-1 Novartis / Alcon Key Intraocular Lenses (IOLs) Products

Table 3-2 Novartis Cataract Surgical Techniques

Figure 3-3 Novartis / Alcon Overview of Surgical Franchise

Table 3-4 Novartis / Alcon IOL Market Strategic Positioning

Table 3-5 Abbott Medical Optics Cataract Products

Table 3-6 Abbott Medical Visiogen’s Synchrony lens Advantages

Table 3-7 Abbott Medical Visiogen’s Synchrony Lens Disadvantages

Figure 3-8 Bausch + Lomb Crystalens® FDA-Approved Intraocular Lens

Figure 3-9 Bausch + Lomb:  Crystalens IOL Features

Figure 3-10 STAAR® Surgical Company nanoFLEX IOL

Figure 3-11 Staar Implantable Collamer® Lens for Quality of Vision

Table 3-12 Staar IOL Products

Figure 3-12 Staar Toric Visual Acuity

Figure 3-13 Hoya Pre-Loaded IOL Delivery System “iSert™

Figure 4-1 Human Eye

Figure 4-2 Staar nanoFLEX

Figure 4-3 Staar nanoFLEX  Collamer has a built in Anti-Reflective Interface

Figure 4-4 Staar Hydrophilic Collamer Ultra-High Water Content Layer On Its Surface Minimizing The Difference In Refractive Index

Figure 4-5 Staar nanoFLEX™ Collamer Percentage of Light Reflectance

Figure 4-6 Staar nanoFLEX™ Collamer Single Piece IOL

Figure 4-7 Staar nanoFLEX™ Collamer Incision Size

Figure 4-8 Staar nanoFLEX™ Collamer Protective Layer

Figure 4-9 Staar Afinity 3-Piece Collamer Aspheric IOL Model CQ2015A Function 4-10 Modulation Transfer Function (MTF) Analysis

Table 4-11 Cataract Symptoms

Table 5-1 AkkoLens Technological Features

Table 5-2 AkkoLens Medical Features

Figure 5-3 Hoya IOL plant in Singapore

Figure 5-4 Novartis / Alcon Positioning in Healthcare

Figure 5-5 Novartis Resource By Segment

Figure 5-6 Novartis Surgical Franchise

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