Linezolid is an antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to other antibiotics. Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA). The main uses are infections of the skin and pneumonia although it may be use for a variety of other infections.
When administered for short periods, linezolid is a relatively safe antibiotic. It can be used in people of all ages and in people with liver disease or poor kidney function. Common adverse effects of short-term use include headache, diarrhea, and nausea. Long-term use, however, has been associated with serious adverse effects such as bone marrow suppression and low platelet counts, particularly when used for more than two weeks. If used for longer periods still, it may cause sometimes irreversible chemotherapy-induced peripheral neuropathy and optic nerve damage, and lactic acidosis (a buildup of lactic acid in the body), all most likely due to mitochondrial toxicity.
As a protein synthesis inhibitor, it stops the growth of bacteria by disrupting their production of proteins, that is, it is a bacteriostatic agent, not bacteriocidal. Although many antibiotics work this way, the exact mechanism of action of linezolid appears to be unique in that it blocks the initiation of protein production, and not one of the later steps. Bacterial resistance to linezolid has remained very low since it was first detected in 1999, although it may be increasing. It is a member of the oxazolidinone class of drugs.
Linezolid was discovered in the 1990s by a team at Pharmacia and Upjohn Company and first approved for use in 2000. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Linezolid costs approximately US$100 per tablet in the United States. Nonetheless, it appears to be more cost-effective than generic alternatives such as vancomycin, mostly because of the possibility of switching from intravenous to oral administration as soon as patients are stable enough, without the need for dose adjustments.
This report provides detailed analysis of worldwide markets for Linezolid from 2011-2015 and provides extensive market forecasts 2016-2021 by region/country and subsectors. It covers the key technological and market trends in the Linezolid market and further lays out an analysis of the factors influencing the supply/demand for Linezolid, and the opportunities/challenges faced by industry participants. It also acts as an essential tool to companies active across the value chain and to the new entrants by enabling them to capitalize the opportunities and develop business strategies.
GCC’s report, Global Linezolid Market Outlook 2016-2021, has been prepared based on the synthesis, analysis, and interpretation of information about the global Linezolid market collected from specialized sources. The report covers key technological developments in the recent times and profiles leading players in the market and analyzes their key strategies. The competitive landscape section of the report provides a clear insight into the market share analysis of key industry players. The major players in the global Linezolid market are Pfizer (USA), Daewoong (Korea), Glenmark (India), Optimus (India), Symed Labs (India), Amoli (India), Runzhong Pharma (China), Hansoh Pharma (China), Shanghai Acebright (China) , among others.
The report provides separate comprehensive analytics for the North America, Europe, Asia-Pacific, Middle East and Africa and Rest of World. In this sector, global competitive landscape and supply/demand pattern of Linezolid industry has been provided.
Part 1. Exclusive Summary
Part 2. Methodology
2.1 Research Methodology
2.2 Geographic Scope
2.3 Years Considered
Part 3. Introduction
3.1 Definition
3.2 Supply Chain Structure
3.2.1 Raw Material Supply
3.2.2 Traders & Distributors
3.2.3 Key Customers
3.3 Manufacture
3.3.1 Manufacturing Process
3.3.2 Production Cost
Part 4. Market Landscape
4.1 Global Linezolid Market Size (Volume) 2011-2016
4.1.1 Overview
4.1.2 Global Linezolid Production
4.1.3 Top 10 Linezolid Companies (Volume Share)
4.2 Global Linezolid Market Size (Value) 2011-2016
4.2.1 Overview
4.2.2 Global Linezolid Production Value
4.2.3 Top 10 Linezolid Companies (Revenue Share)
Part 5. Segmentation by Products
5.1 Type 1
5.2 Type 2
5.3 Type 3
Part 6. Segmentation by End-users
6.1 Customer Segment 1
6.2 Customer Segment 2
6.3 Customer Segment 3
6.4 Customer Segment 4
Part 7. Geographical Segmentation
7.1 North America Linezolid Market
7.1.1 North America Market Overview
7.1.2 North America Price & Margin
7.1.3 North America Trade Balance
7.2 EMEA Linezolid Market
7.2.1 EMEA Market Overview
7.2.2 EMEA Price & Margin
7.2.3 EMEA Trade Balance
7.3 Asia Pacific Linezolid Market
7.3.1 Asia Pacific Market Overview
7.3.2 Asia Pacific Price & Margin
7.3.3 Asia Pacific Trade Balance
Part 8. Market Forecast
8.1 Market Size by Volume 2016-2021
8.1.1 North America
8.1.2 EMEA
8.1.3 Asia-Pacific
8.1.4 RoW
8.2 Market Size by Value 2016-2021
8.2.1 North America
8.2.2 EMEA
8.2.3 Asia-Pacific
8.2.4 RoW
8.3 Regional Consumption Forecast
8.3.1 North America
8.3.2 EMEA
8.3.3 Asia-Pacific
8.3.4 RoW
8.4 Consumption Forecast by End-users
8.5 Consumption Forecast by Products
Part 9. Company Profiles
9.1 Company A
9.1.1 Overview
9.1.2 Products Offered
9.1.3 Business Performance
9.2 Company B
9.3 Company C
9.4 Company D
Part 10. Market Dynamics
10.1 Market Drivers
10.2 Market Constraints
10.3 Market Strategies
Part 11. Competitive Landscape
11.1 Mergers & Acquisitions
11.2 New Product Launches
11.3 Expansions
11.4 Other Developments
Part 12. Appendix
Disclaimer
Analysts CertificationFigure Global Production 2011-2016
Figure Global Production Value (M USD) 2011-2016
Figure Top 10 Players Revenue Share 2015
Figure Regional Production 2015
Figure Regional Production Value (M USD) 2015
Figure Global Consumption by End Market 2015
Figure Linezolid Product
Figure Supply Chain Structure of Linezolid
Table Raw Materials Used for Linezolid Production
Table Traders & Distributors of Linezolid
Table Key Customers of Linezolid
Figure Linezolid Manufacturing Process Flow
Figure Linezolid Production Cost Structure
Figure Global Linezolid Market, Growth Rate
Table Global Key Vendors Production 2011-2016
Table Global Key Vendors Production Market Share 2011-2016
Figure Global Production, Capacity Utilization 2011-2016
Figure Top 10 Companies Market Share Trends
Table Global Top 10 Vendors Production 2011
Table Global Top 10 Vendors Production 2012
Table Global Top 10 Vendors Production 2013
Table Global Top 10 Vendors Production 2014
Table Global Top 10 Vendors Production 2015
Table Global Top 10 Vendors Production 2016
Figure Global Linezolid Market (M USD), Growth Rate & CAGR
Table Global Key Vendors Production Value (M USD) 2011-2016
Table Global Key Vendors Production Value Market Share 2011-2016
Figure Top 10 Player Market Share Trends
Table Global Top 10 Vendors Production Value (M USD) 2011
Table Global Top 10 Vendors Production Value (M USD) 2012
Table Global Top 10 Vendors Production Value (M USD) 2013
Table Global Top 10 Vendors Production Value (M USD) 2014
Table Global Top 10 Vendors Production Value (M USD) 2015
Table Global Top 10 Vendors Production Value (M USD) 2016
Figure Prices of Major Players 2016
Figure Gross Margin of Major Players 2016
Table Types of Linezolid
Figure Global Production Market Share of Linezolid by Types in 2015
Table Type 1 Linezolid Production 2011-2016
Table Type 1 Linezolid Price Trends 2011-2016
Table Major Manufacturers of Type 1 Linezolid
Table Type 2 Linezolid Production 2011-2016
Table Type 2 Linezolid Price Trends 2011-2016
Table Major Manufacturers of Type 2 Linezolid
Table Type 3 Linezolid Production 2011-2016
Table Type 3 Linezolid Price Trends 2011-2016
Table Major Manufacturers of Type 3 Linezolid
Figure Global Linezolid Market by Key Customer Segments 2015
Table Linezolid Consumed for Customer Segment 1
Table Key Customers of Linezolid
Table Linezolid Consumed for Customer Segment 2
Table Key Customers of Linezolid
Table Linezolid Consumed for Customer Segment 3
Table Key Customers of Linezolid
Figure Global Linezolid Market Segmentation by Geography 2015
Figure North America Linezolid Capacity & Production 2011-2016
Figure North America Linezolid Revenue (M USD) 2011-2016
Figure North America Linezolid Price & Margin 2011-2016
Table North America Linezolid Trade Balance
Figure North America Linezolid Self-sufficiency
Figure EMEA Linezolid Capacity & Production 2011-2016
Figure EMEA Linezolid Revenue (M USD) 2011-2016
Figure EMEA Linezolid Price & Margin 2011-2016
Table EMEA Linezolid Trade Balance
Figure EMEA Linezolid Self-sufficiency
Figure Asia Pacific Linezolid Capacity & Production 2011-2016
Figure Asia Pacific Linezolid Revenue (M USD) 2011-2016
Figure Asia Pacific Linezolid Price & Margin 2011-2016
Table Asia Pacific Linezolid Trade Balance
Figure Asia Pacific Linezolid Self-sufficiency
Figure Global Production Volume Forecast 2016-2021
Table Global Production Volume 2016-2021
Table Global Production Volume Share 2016-2021
Figure North America Linezolid Production Volume Forecast
Figure Global Production Value (M USD) 2016-2021
Table Global Production Value (M USD) 2016-2021
Table Global Production Value Share 2016-2021
Figure North America Linezolid Production Value (M USD) Forecast
Figure Regional Consumption 2021
Table Consumption Volume by Region 2016-2021
Table Consumption Volume Share by Region 2016-2021
Figure North America Consumption 2016-2021
Figure Consumption by Key Customer Segments 2021
Table Global Linezolid Market by Customer Segments 2016-2021 (Volume)
Table Global Linezolid Market by Customer Segments 2016-2021 (Share)
Figure Consumption by Types 2021
Table Global Consumption Volume by Types 2016-2021
Table Global Consumption Volume Share by Types 2016-2021
Table Financial Performance 2011-2016
Figure Market Share Trend 2011-2016
